NOD2 monoclonal antibody, clone 2D9
产品名称： NOD2 monoclonal antibody, clone 2D9
英文名称： NOD2 monoclonal antibody, clone 2D9
产品编号： MAB2303
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant NOD2.
- Immunogen:
- Recombinant protein corresponding to amino acids 28-301 of human NOD2.
- Host:
- Mouse
- Reactivity:
- Human, Primates
- Specificity:
- This antibody is specific to NOD2 protein.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In Tris-glycine, 150 mM NaCl
- Storage Instruction:
- Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis.
Ogura Y, Lala S, Xin W, Smith E, Dowds TA, Chen FF, Zimmermann E, Tretiakova M, Cho JH, Hart J, Greenson JK, Keshav S, Nunez G.Gut. 2003 Nov;52(11):1591-7.
- 2.
- Crohn's disease and the NOD2 gene: a role for paneth cells.
Lala S, Ogura Y, Osborne C, Hor SY, Bromfield A, Davies S, Ogunbiyi O, Nunez G, Keshav S.Gastroenterology. 2003 Jul;125(1):47-57.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of NOD2 in 50 ug of HT-29 cell lysate with NOD2 monoclonal antibody, clone 2D9 (Cat # MAB2303).
- Entrez GeneID:
- 64127
- Gene Name:
- NOD2
- Gene Alias:
- ACUG,BLAU,CARD15,CD,CLR16.3,IBD1,NLRC2,NOD2B,PSORAS1
- Gene Description:
- nucleotide-binding oligomerization domain containing 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
- Other Designations:
- NLR family, CARD domain containing 2,NOD-like receptor C2,OTTHUMP00000164224,caspase recruitment domain family, member 15,caspase recruitment domain protein 15,inflammatory bowel disease protein 1,nucleotide-binding oligomerization domain 2,nucleotide-bin
- Related Disease
- Abscess
- Acquired Hyperostosis Syndrome
- Acute Disease
- Adenocarcinoma
- Anus Diseases
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Arthropathy, Neurogenic
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation
- Autoimmune Diseases
- Bacteremia
- Bacterial Infections
- Behcet Syndrome